Tricor is a lipid-lowering drug that is used to treat dyslipidemia, including in patients with diabetes mellitus (against the backdrop of ineffective diet therapy and increased physical activity). Reduces the content of fibrinogen and atherogenic fractions of cholesterol in the blood (LDL and VLDL), enhances the excretion of uric acid. In patients with elevated fibrinogen levels treated with fenofibrate, there was a significant decrease in this index, as well as in patients with elevated lipoprotein levels. When treating by fenofibrate, there is a decrease in the concentration of C-reactive protein and other markers of inflammation. For patients with dyslipidemia and hyperuricemia, the additional advantage is that fenofibrate has a uricosuric effect, which leads to a decrease in the uric acid concentration by approximately 25%.
Indications for use Tricor:
Preparation Tricor is prescribed for hypercholesterolemia with ineffectiveness of the diet; Hypertriglyceridemia with little effect on the diet; secondary hyperlipoproteinemia.
How to use Tricor:
Standard dosing of the drug Tricor is 1 tablet / 1 time per day. You can’t chew the pill, it is washed down with a glass of water. It is important not to forget to follow a special diet.
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Side effects of Tricor:
Reception of the drug Tricor can be accompanied by side effects, namely: epigastric pain, nausea, alopecia, vomiting, photosensitivity, pancreatitis, sexual dysfunction, diarrhea, the formation of biliary calculi, flatulence, increased hemoglobin concentration; diffuse myalgia; headache; hepatitis; venous thromboembolism; myositis; increased urea levels; muscle weakness; excessive activity of hepatic transaminases; skin itching; reaction of photosensitivity; pulmonary embolism; an increase in the number of leukocytes; increased activity of CK; interstitial pneumopathy; rhabdomyolysis; muscular spasms; skin rash; increased levels of creatinine; hives.
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Contraindications for Tricor:
The drug Tricor is not prescribed for: liver failure; diseases of the gallbladder; lactase insufficiency; renal failure with QC<20 ml / min; сongenital galactosemia; hypersensitivity to fenofibrate; pregnancy; hypersensitivity to auxiliary components; cirrhosis of the liver; allergies to peanuts; allergies to soy lecithin; congenital fructosemia; photo-sensitization during therapy with fibrates in the anamnesis; testimony in children, adolescents; insufficiency of sucrose-isomaltase; lactation.
With caution, the drug Tricor is prescribed for: hypothyroidism; alcohol dependence; indications in the elderly; therapy with HMG-CoA reductase inhibitors; hereditary muscle pathologies; treatment with oral anticoagulants.
Pregnancy and Tricor:
Application Tricor during pregnancy is contraindicated. The risk to the fetus is theoretically absent, but there is no clinical evidence for this.
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Interaction with other drugs Tricor:
Tricor enhances the effect of oral anticoagulants, which is why bleeding may occur.
With a simultaneous appointment with cyclosporine, a reversible decrease in the excretory function of the kidneys is possible.
Simultaneous application of “Tricor” and other derivatives of fibrous acid increases the risk of toxic effects on skeletal muscles, up to the development of rhabdomyolysis.
In official documents, cases of overdose with Tricor tablets are not fixed. In such cases, the conduct of hemodialysis is inexpedient, there is no specific antidote. Therapy is prescribed in accordance with the symptoms.