Trental is a drug from the group of angioprotectors, which aims to improve microcirculation (blood circulation in capillaries). The drug contains a substance of pentoxifylline.
Indications for use
Trental is prescribed for a number of diseases, including pathology of the spine. These include the following:
Atherosclerosis of the spine;
Fracture of the spine;
Severe contusions of the spine and its structures.
Trental is contraindicated under the following conditions and diseases:
Children under 18 years of age;
Tendency to bleeding;
Myocardial infarction of the acute phase;
Low blood pressure (hypotension);
Ulcer of stomach and duodenum;
Allergy to the drug and its components;
Rhythm disorders of the heart;
Surgery less than a week ago before starting treatment with Trental
The principle of action of Trental
Once in the systemic circulation, Trental is immediately sent to the affected capillaries. So the active ingredient of the drug restores the elasticity of the walls of the erythrocytes (red blood cells), inhibits the increased clotting of platelets, improves the flow properties of blood by decreasing its viscosity. The drug also expands the blood vessels by reducing them to spasm.
Trental normalizes metabolism in tissues of the spine and its structures, restores gas exchange. It restores the flow of blood through the vessels of the spinal cord after a stroke, and also restores nerve conduction, at the expense of proper nutrition and blood supply of nerve endings in the affected area.
Method of reception of Trental
Trental in tablet form
Tablets of Trental should be taken orally without chewing or breaking, after ingestion of 100-400 mg 2-3 times per day. The maximum daily dosage is1200 mg. A course of treatment is chosen individually and can range from 2 weeks to several months.
Trental in the form of solution for injection
The solution for injection is intended for intravenous bolus or infusion. If you want to prepare a dropper, you should mix the physiological solution or 5% glucose with 1-6 capsules of Trental and take this mixture during 1 hour. The multiplicity of reception is 1-2 times a day. The maximum daily dosage is 12 vials (1200 mg).
Stream infusion is injected at the dosage of 1 ampoule for 5 minutes 1-2 times a day.
Side effects of Trental
In extremely rare cases, Trental can cause side effects. The main ones include:
Vomiting accompanied by nausea;
Diarrhea, constipation or alternating;
Angina (short-term compressive pain in the chest);
Lowering of blood pressure;
Itching of the skin;
Insomnia at night and drowsiness by day;
If you experience side effects, you should stop taking the drug, contact your doctor, perform gastric lavage and, if necessary, take symptomatic drugs.
Failure to comply with the recommended dosage of the drug may develop the following symptoms:
Vomiting with coffee grounds (a sign of stomach bleeding);
The decrease of blood pressure;
The increase in body temperature.
If you experience signs of overdose with Trental, you must perform gastric lavage, take symptomatic drugs and intestinal adsorbents.
Trental is contraindicated during pregnancy and during breastfeeding. If necessary, treatment with Trental should be discontinued during breastfeeding.
Children under 18 years shouldn’t use this drug because there are no reliable data on its impact on child development.
The alcoholic beverage does not affect the properties of Trental.