Capsules of Retrovir can be bought on our site, it is prescribed for children from 3 years and adults, the drug is not prescribed to younger children due to difficulties with swallowing. Retrovir should be consumed without chewing.
Children with weight of 30 kg and adults are prescribed Retrovir 300 mg 2 times a day, children from 21 kg taken 200 mg of the drug 2 times a day, children over 14 kg taken 100 mg in the morning and 200 mg in the evening, children from 8 kg take 100 mg of the drug 2 times a day .
During pregnancy capsules are taken from the 14th week before the childbirth at the dosage of 500 mg/day.
The solution for inside use is prescribed to children from the first 12 hours of life. The exact dose of the medication is measured and used using dosing syringe. 5 ml of solution contains 50 mg of zidovudine. After application, the dosing syringe should be washed thoroughly with clean water.
The drug is prescribed to children weighing 30 kg and adults at the dosage from 250 to 300 mg 2 times a day, children weighing from 9 to 30 kg take 9 mg/kg 2 times day, from 4 to 9 kg – 12 mg/kg 2 times a day. Newborn have the injections of solution of Retrovir at the dosage of 2 mg/kg every 6 hours for 6 weeks.
Parenteral solution is introduced intravenously in diluted form for 1 hour. Parenteral method of administration can be used only when a patient can take the capsules and oral solution inside.
The infusion solution is diluted with 5% p-rum dextrose to obtain a concentration of 2 or 4 mg/ml.
Adults and children over 30 kg are injected intravenously at the dosage 1 mg/kg every 4 hours. Children from 3 months to 12 years have the injection at the dosage of 80-160 mg/m2 every 6 hours.
During the childbirth it is injected I/V at the dosage of 2mg/kg over 1 h, with subsequent infusion until the dressing of the umbilical cord.
In case of the renal disease they use the drug at the dosage of 1 mg/kg 3-4 times a day. In the terminal stage, Retrovir is used at the dosage of 100 mg every 6-8 h.
In case of the violation of the liver and the hemopoietic system, the dose and frequency of application are determined individually according to the results of laboratory tests of blood.
Side effects and actions of drugs.
Therapy with Retrovir often provokes vomiting, dizziness, anemia , neutropenia, leukopenia, hyperlactatemia, headache, diarrhea, hyperbilirubinemia, myalgia.
In the background of the use of medication it may develop: thrombocytopenia, pancytopenia, dyspnoea, rash, itching, myopathy, fever, fibromyalgia, asthenia, flatulence.
Rarely treatment with Retrovir provokes breach of taste, a red blood cell aplasia, increased sweating, aplastic anemia, flu-like syndrome, lactic acidosis, anorexia, accumulation of adipose tissue, paresthesia, drowsiness, convulsions, thought disorder, anxiety, depression, cardiomyopathy, cough, pigmentation of the mucous membranes of the mouth, skin and nails, hepatomegaly with stenosis, pancreatitis, frequent urination, pain in the chest, gynecomastia, insomnia.
Drug contraindications and negative properties.
The use of Retrovir is prohibited if you are allergic to its components.
The drug is contraindicated in case of neutropenia and hypogemoglobinemya.
Retrovir is taken with caution in case anemia, liver failure, dysfunction of the bone marrow in the treatment of elderly patients.
The use of the drug is allowed to the 14 weeks according to indications
The treatment with Retrovir is contraindicated during breastfeeding.
Interaction with other drugs.
Phenytoin concentration decreases under the influence of Retrovir.
Excretion of Retrovir slows down under the influence of probenecid and other agents metabolized in the liver (codeine, acetylsalicylic acid, cimetidine, Dapsone, lorazepam, indomethacin). Retrovir can be bought on our website in any quantity.
A long-term therapy of Retrovir with atovaquone should be held with caution due to violations of the pharmacokinetics of the first one.
The bioavailability of the Retrovir is reduced under the action of clarithromycin, the interval between the use of funds must be at least 2 hours.
The use of Retrovir with ribavirin may cause pronounced antagonism, that’s why it is contradicted to combine the drugs.
The pharmacokinetics of stavudine changes in the case of treatment with Retrovir.
The excretion of Retrovir is increased with the use of valproic acid, methadone and fluconazole.
Overdose. The symptoms and consequences.
An overdose of Retrovir may cause anxiety, vomiting, headache, fatigue, hematological disorders.
Form of issue. Packing.
Retrovir comes in the form of capsules, solution for inside use and solution for infusion which we have in stock and you can buy them on our website.
Each white capsule contains 100 mg of zidovudine and has the inscription “GSYJU” in black ink. The drug is released in blister packs with 10 tablets in each blister. The pack consists of 10 blisters.
The solution for oral use of light yellow colour with strawberry flavour contains 50 mg of zidovudine and 5 ml of medication dispensed in bottles of 200 ml. The pack consists of 1 bottle adapter and dosing syringe.
Colorless, clear solution for injection/consists of 10 mg of zidovudine in 1 ml (200 mg vial). The drug is dispensed in bottles of 20 ml. A pack consists of 5 glass vials with a medicament.