In medical practice, non-steroidal anti-inflammatory drugs (NSAIDs) are given special importance for the treatment of diseases that are accompanied by constant pain. Among them, the medicinal preparation Motrin can be considered as a good reason. Indications for the use of this medication, in the first place, are aimed at eliminating painful sensations in inflammation of the joints, muscles, nerve endings.
It is known that the cause of many inflammatory reactions (for example, dysmenorrhea), pain, fever, are prostaglandins. Motrin is able to inhibit the activity of certain enzymes that promote the formation of substances that are the precursors of prostaglandins. This is the main mechanism of the effect of this medication. The medicine has analgesic, anti-inflammatory and antipyretic properties.
Motrin, recommended by doctors as a reliable medication, perfectly copes with inflammatory reactions in the tissues, helps to cope with the morning stiffness in the joints. Also, the drug is able to suppress the formation of thrombi in blood vessels.
With internal use, the drug is completely absorbed in the gastrointestinal tract, getting into the blood. It is believed that with simultaneous intake of food and medicine, the rate of its absorption is significantly reduced. The decomposition of Motrin occurs in the hepatic, after which the metabolic products are excreted in the urine.
In metabolic and inflammatory joint diseases (osteoarthritis, rheumatoid and rheumatoid arthritis), doctors often recommend the use of Motrin. Indications for the use of this drug apply to the treatment of inflammation and pain in joints with psoriasis, gout, severe pain in the spine with Bekhterev’s disease. The drug is successfully used for pain in the muscles, ligaments, tendons that have arisen against a background of various injuries. Motrin is used in gynecology with inflammation of the female genitalia, severe pain during menstruation, as well as with headaches and acute dental pains. As a febrifuge, the drug helps at high temperature.
This medication requires special attention. With all its positive therapeutic properties Motrin has a large number of side effects that should be taken into account. The drug may cause side effects in the organs of the gastrointestinal tract. These are nausea, vomiting, diarrhea, mucous membrane disorders of the stomach with further formation of erosions, ulcers. Sometimes Motrin has an adverse effect on the hepatic and biliary tract.
Patients assigned to receive this medication often after long-term use observed negative phenomena from the nervous system: dizziness, excessive excitability, or vice versa drowsiness during the day, impaired vision.
Also, doctors who prescribe Motrin should consider possible side effects from the hematopoiesis system. If there is a decrease in red blood cells, a decrease in hemoglobin (anemia), it is required to stop taking the drug. With a decrease in the number of granular white blood cells (agranulocytosis), the immune system suffers. Thus the person becomes defenseless before various infections.
Of course, such a broad list of side effects may cause some concern, but it should be borne in mind that the negative manifestations can only be long-term use of the drug. Contraindications to receiving Motrin: ulcerative colitis, gastric and duodenal ulcers, lesions of the optic nerve, polypoid rhino-sinusitis (a type of rhinitis), asthma, severe dysfunction of hepatic and kidney, blood diseases, pregnancy, intolerance to ingredients in the preparation. When using a medicament as an ointment, care should be taken not to apply it to damaged skin. Use it carefully during breastfeeding.
Given the significant number of side effects and contraindications, self-medication is not recommended. Only an experienced doctor will be able to pick up the necessary dosage of Motrin and set the duration of the course of treatment on the basis of evidence of human health.