Motilium is used for the treatment of sickness and vomiting and relieving such symptoms as bloating, fullness, acid reflux and gas, caused by overeating. Motilium 10 can be also used to relieve symptoms of sickness caused by some drugs, such as anti-cancer and Parkinson’s disease medication. Moreover, Motilium can increase the release of breast milk.
How does the drug acts?
Motilium 10 contains the antiemetic domperidone, which prevent you from nausea by blocking the action of the dopamine. This stops messages sent from your upset stomach being received by certain brain receptors, impeding the brain inducing the vomiting reaction. Motilium 10 blocks the same receptors in the upper digestive tract, which relieves dysmobility (the condition when food processing slows down triggering inconvenient symptoms). Motilium 10 normalizes the rate of muscle contraction and stomach relaxation, which allows pushing food through your digestive system and impedes vomiting.
The main ingredients of Motilium
The active component of Motilium is antiemetic medicine domperidone 10mg, which relieves symptoms of sickness and vomiting. Moreover, Motilium contains lactose, starch, microcrystalline cellulose, pregelatinized potato starch, povidone, magnesium stearate, hydrogenated vegetable oil, sodium lauryl sulfate and hypromellose.
Treatment of nausea
Domperidone (the main active component of Motilium) is used for the treatment of sickness and vomiting, as well as the other symptoms of stomach diseases, as well bloating, fullness, acid reflux and gas, which cause inconvenience. Motilium is an antiemetic drug that acts by preventing the action of the dopamine in the brain and upper intestine, which impedes vomiting and normalizes the function of the digestive tract.
Even though the adverse effects happen rarely, some of them are more usual (for example, head and abdominal pain and dryness in the mouth. As Motilium can’t cross the blood brain barrier, it never leads to the extrapyramidal adverse effects (such as convulsion and involuntary movements, which can be related to some dopamine blocking medications. But at the same time, Motilium can increase the release of the hormone prolactin, which improves the secretion of breast milk, and therefore cause gynaecomastia (increase in the size of male breast) and temporary amenorrhoea (absence of menstruation). These adverse effects will disappear as soon as you stop the treatment.
You must avoid using Motilium in the following cases:
hypersensitivity to domperidone or any other drug ingredients
have an lactose intolerance or malabsorption
galactosaemia (genetic metabolic disorder, which affects a person’s ability to metabolize the sugar galactose)
are taking another drug, which can interact with Motilium (for example, ketoconazole, fluconazole or voriconazole);
antibiotics that contain erythromycin, clarithromycin or telithromycin;
amiodarone, used for the treatment of increased heart rate.
gastrointestinal bleeding or mechanical obstruction
kidney / renal dysfunction
pituitary tumor, which leads to the excessive production of prolactin.
The use of Motilium
You must take Motilium with a full glass of water 15-30 minutes before eating. The patients older than 16 can take the pill 3 times a day before sleep. To increase release of breast milk, you should take up to 2 pills 4 times a day.
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