Lopressor HTC is a beta-blocker. According to the results of the animal studies, it affects only the beta1 adrenoreceptors, mainly located in cardiac muscle. But at higher doses, this drug also impedes the production of beta2 adrenoreceptors, mainly located in the bronchial and vascular muscles.
Clinical researches have confirmed the beta-blocking activity of metoprolol in male patients, reflected in (1) decrease in heart rate and cardiac output, (2) decrease of systolic blood pressure during exercise, (3) prevention of isoproterenol-induced tachycardia, and (4) decrease of reflex orthostatic tachycardia.
This medicine can be taken orally, irrespective of the mealtime. You should take it regularly to achieve the maximum effect. The urination can be increased during the treatment. To prevent sleeping issues, the drug must be taken 3-4 hours before sleep. If you skipped the dose, take it as soon as you remember.
Tell your doctor if you’re pregnant, planning a pregnancy or breastfeeding.
In some patients, Lopressor HTC can cause some adverse effects, such as vision impairment, stiffness, hemorrhage, restlessness, vertigo, dryness in the mouth, hallucination, cramps, head pain, diarrhea, vertigo, etc.
You should avoid certain drugs during the treatment with Lopressor (such as Diltiazem, Arsenic Trioxide, Fenoldopam, Levomethadyl, Proscillaridin, Ouabain, Lidocaine, Rivastigmine and Digitalis), as they can cause adverse effects. It is important to consult your doctor about all the drugs you’re taking. The same applies to the prescription and over-the-counter medicines, herbal supplements and vitamins.
Before starting the treatment, inform your doctor if you have allergy to metoprolol or hydrochlorothiazide, as well as the other thiazide diuretics. This drug may include some inactive components that can lead to the allergic reactions or other complications. Ask your doctor for more information.
This drug must not be used if you have certain health problems. Before starting the treatment, inform your doctor if you have: heart rhythm disorders (irregular heartbeat, second- or third-degree atrioventricular block, sick dysfunction), nonpassage of urine (anuresis).
Before taking the drug, inform your physician if you suffered from the following diseases: blood circulation diseases, PCC, breathing issues (for example, asthma or chronic bronchitis), hyperthyroidism (a condition in which the thyroid overproduces hormones), liver or kidney dysfunction, lupus, severe allergic reactions, mental diseases, gout, dehydration (deficit of total body water), electrolyte imbalance and myasthenia gravis.
If you’re going to have an operation, inform your doctor or dentist that you’re taking this drug.
If you suffer from diabetes, this drug may mask the increased heartbeat you would usually feel when your blood sugar reduces (in case of hypoglycemia). Other symptoms of hypoglycemia, such as vertigo and perspiration, are unaffected by this medication. This drug may also make it more difficult to control your blood sugar level. Therefore, you should make the blood tests regularly. Inform your doctor at once if you experience increased thirst or frequent urination. Perhaps, your physician will have to adjust your diabetes treatment, workout program or diet.