The use of Cleocin.
Pregnant women may take Cleocin if the expected effect of treatment outweighs the potential risk to the fetus and child. The category of risk to the fetus during the reception of Cleocin by pregnant woman according to FDA — B (animal studies have not identified risks of negative impact of Cleocin on the fetus, there haven’t been adequate studies of pregnant women).
Cleocin is excreted in breast milk after oral or parenteral reception. There are no data on the penetration of Cleocin in breast milk in intravaginal or external. There is evidence that concentration of Cleocin in breast milk reaches the values of 0.7 to 3.8 mcg/ml. Therefore, nursing mothers should be cautious while taking the drug. Cleocin can be on the website.
Cleocin gel is not recommended for children under 12 years. Cleocin capsules should not be given to children under 8 years weighing less than 25 kg. It is not recommended for children under three years to have intravenous or intramuscular injections of Cleocin containing benzyl alcohol. Cleocin in any form is not used to infants up to one month.
Diarrhea, hemorrhagic and pseudomembranous colitis are caused by taking Cleocin
Cleocin may be a cause of a number of so-called “drug diseases” of the digestive tract. Over-reliance on antibiotics even for minor respiratory infections, unreasonable and irrational prescription of antibiotics can promote the development of antibiotic associated diarrhea. Unfortunately, when a doctor prescribed antibiotics, they don’t always take into account their impact on the microflora inhabiting the intestine. Antibacterial drugs inhibit the growth of not only pathogens but also the normal microflora. The result of the multiply saprophytic microbes that acquire pathogenic properties. They include Staphylococcus, Proteus, yeast, enterococci, Pseudomonade aeruginosa, Klebsiella.
Antibiotic associated diarrhea is often caused by commonly used drugs in outpatient and inpatient practice, such as Cleocin, lincomycin, ampicillin, penicillin, cephalosporins, tetracycline, erythromycin. The prescription of an antibiotic is not critical in this way. The symptoms of antibiotic of associated diarrhea usually appear during treatment and 30% of patients notice them after 110 days after termination. Most researchers believe that the direct etiological factor of antibiotic associated diarrhea is, in particular, Clostridium difficile.
According to various sources, antibiotic associated diarrhea occurs in 20-30% of patients taking Cleocin which you can buy on our website. Antibiotic associated diarrhea can occur in several clinical forms. The easiest and most common form is the moderate malaise — a complex of any symptoms of diarrhea that do not fit the classical definition of an antibiotic associated diarrhea. The main sign of the actual antibiotic associated diarrhea is a diarrheal syndrome in the absence of pain, intoxication and dehydration. The most severe forms of the disease are antibiotic-associated colitis, segmental hemorrhagic colitis, and pseudomembranous colitis. Infectious factor plays an important role in the pathogenesis of these diseases, in particular, Clostridium difficile, Staphylococcus aureus, Salmonella spp., Clostridium perfringens (type A), Candida spp, Klebsiella oxytoca.
Patients older than 60 years experience antibiotic associated colitis and diarrhea caused by Clostridium difficile which occur more frequently and can be more severe, so you need to closely monitor the condition of patients and frequency of stool, to avoid the development of diarrhea.
The order of application of clindamycin and dosage
The duration of treatment and dose is established by a physician taking into account the specifics of the disease and its severity. Usually it is used:
for the treatment of female diseases (dosage form “vaginal cream” and “suppository for vaginal use”): 100 mg intra vaginally at bedtime for 3-7 days
for the treatment of skin diseases; a thin layer of gel on clean, dry skin in the affected area
intramuscularly or intravenously twice a day:
for adults at a dose of 300 mg two times a day, 1,2 g up to four times a day,
children take 10 to 40 mg per kg of weight per day in 3-4 reception