The drug Cardura is designed to lower blood pressure and treat benign prostatic hyperplasia.
Cardura is a selective blocker of alpha1 adrenergic receptors.
The main active ingredient of the drug, doxazosin, blocks alpha 1 adrenergic receptors located after synapses, which has the effect of reducing the overall atrial resistance, thereby affecting blood pressure.
The effect of the drug is 2-6 hours after taking and acts during the day. The pressure does not vary from the position of the patient’s body. To the great joy of those suffering from high blood pressure, the drug is not addictive and has the same effect after a long time, as well as at the beginning of taking the remedy.
When the drug is administered, the heart palpitations and renin activity of the plasma in the blood rarely develop.
Cardura also acts on the exchange of lipids, reducing the risk of developing coronary heart disease. Increases sensitivity to insulin in violation of its production in the body, does not affect the erection.
For the treatment of high blood pressure
Usually doxazosin is an independent drug in the treatment of hypertension. In case of its insufficient effectiveness, additional therapy with diuretics of thiazide group, calcium ion antagonists, beta-adrenoreceptor blockers, angiotensin-converting factor inhibitors is prescribed.
For maintenance therapy for benign prostatic hyperplasia.
It is assigned in complex therapy with a delay in urine and in the presence of signs of BPH. Even if the blood pressure is not increased. Lowering of the pressure will be very slight.
In the presence of allergic reactions to the drug or its ingredients.
Application in pregnancy and lactation
It is not recommended to use the drug during these periods, because the effect of the drug on the course of pregnancy and the fetus itself, as well as the effect on breastfeeding, have not been studied.
Dosing and Administration
Usually, the drug is administered in the morning or evening. The first reception should be done at night.
When hypertension is taken internally to 16 mg (maximum dose) of the drug once. Therapy should be started with 1 mg within a week or two. For the next week or two, you can increase the dose to 2 mg. Further, the dosage, depending on the need and indications, is increased according to the same scheme.
The most optimal dose and good effectiveness of the drug is 2-4 mg per day.
With the complex treatment of prostatic hyperplasia, the initial dose is the same – 1 mg. Further dosage depends on the patient’s condition and drug tolerance. The increase in doses occurs according to the scheme described above. In this case, the maximum dosage is 8 mg.
In case of an overdose of the drug, a sharp and steady decrease in blood pressure is observed. In this case, the person is laid in such a way that the legs are above the head.
In patients with elevated blood pressure, pressure fluctuations and fainting, headaches, dizziness, drowsiness, nausea, gastrointestinal upset, abundant nasal discharge, asthenia, and high fatigue were noted.
Patients with dysplasia report the same adverse reactions. Sometimes there are other, nonspecific effects: dry mouth, gynecomastia, various disorders in the gastrointestinal system.
There can be also purpura, leukopenia, postural hypotension, muscle contractions, pain in the joints and muscles, muscle weakness, sleep disorders, anorexia, hyperexcitability, erectile dysfunction, anxiety, depression.
Less common are cough, bronchospasm, nosebleeds, breathing disorders, itching, rash, baldness. The bladder reacts by hematuria, dysuria, urination disorders, urinary incontinence, nicturia, frequent urination, weight gain, tidal flare, pain.