The variety of different microbes and bacteria affects the human body, forcing scientists and physicians to constantly seek new forms of antibacterial drugs, because it is sometimes impossible to do without them. Antibiotics may be of semi-synthetic or natural origin. They all have the ability to inhibit the growth and reproduction of pathogenic bacteria, therefore, are widely used in the treatment of infectious diseases, when other medicines are ineffective. In particular, one of the most common antimicrobials is Biaxin. The instruction notes that this is a semi-synthetic antibiotic which belongs to the group of macrolides.
Used in medical practice, macrolides are different from other groups of antibiotics that are able to inhibit the synthesis of proteins within microbial cells. It was repeatedly noted: when microorganisms develop resistance resistance to chloramphenicol, tetracycline and drugs of the penicillin group, they become sensitive to macrolides. In relation to the human body these antibiotics, including Biaxin, are considered the least toxic antibiotics. Macrolides have anti-inflammatory, bacteriostatic and even immunomodulatory effects.
Biaxin reveals the high impact of the activity against a large number of microorganisms and intracellular parasites. These include a number of gram-positive and gram-negative bacteria, many anaerobes, protozoa, virtually all mycobacteria. During the oral administration, Biaxin is quite rapidly absorbed from the gastrointestinal tract. Moreover, its concentration is much higher in biological tissues and fluids of the body than in blood plasma. Further the drug is excreted in the urine, and products of metabolism.
Biaxin is released in the form of coated tablets. One tablet contains 250 mg of clarithromycin, the active substance of the drug. Due to the high demand of this antibiotic throughout the world, many manufacturers of pharmaceuticals release Biaxin under other names: Fromilid, Lecker, Klerimed, Klacid, Klabax, Binocular. The dosage form of the medicament may also be different. For example, there may be granules for the preparation of suspensions or liquid for injections. Regardless of the name and method of production, the product has high efficiency, its indications for use remain unchanged.
Indications for use
Indications for use of Biaxin are inflammatory diseases that are caused by microorganisms which are sensitive to the medication. This primarily infections of ENT-organs, upper and lower respiratory tract: sinusitis, otitis, tonsillitis, pharyngitis, acute bronchitis, bacterial and atypical pneumonia. Also this medication is used to treat infections of the skin and soft tissues (furunculosis, folliculitis, impetigo), chlamydia, Lyme disease. This drug is prescribed for the prevention of mycobacterial infections of AIDS patients. In addition, Biaxin is widely used in gastroenterology in the treatment of patients with gastric ulcer and duodenal ulcer caused by the bacterium of Helicobacter pylori.
How to use
According to the instructions, the drug is taken in the morning and evening at the dosage of one tablet (250 milligram), but depending on the nature of the disease the exact dosage and duration of treatment is prescribed by your doctor.
Contraindications and side effects
The medicine can cause some side effects – nausea, diarrhea, dizziness, and insomnia. Also it may cause allergic reactions (skin rash, urticaria) and may change the sense of taste.
It is necessary to take into account some contraindications to Biaxin. The instruction notes that this medication is prohibited in case of hepatitis, severe hepatic insufficiency, porphyria, hypersensitivity to macrolide antibiotics. It is also not recommended to take the drug in the first trimester of pregnancy, during breastfeeding, and by children under 12 years of age.
Combination with other drugs
When Biaxin is taken with carbamazepine and theophylline it may cause an increase in the concentration of the latter substances in the blood plasma.
Thus, Biaxin is an effective antibacterial drug. However, as with all antibiotics, this drug can only be used on the advice of a doctor, so do not practice self-medication.